new gbl for sale CAS 7331-52-4 & CAS 96-48-0

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(S)-3-Hydroxy-gamma-butyrolactone is an important intermediate in organic synthesis and an important chiral pool. It is mainly used in the synthesis of some natural products and some bioactive chiral drugs or antibiotic chiral drugs. For example, it is a key intermediate in synthesis of nerve regulator (R)-GABOB and brain metabolic accelerant S-oxiracetam (S-ORC). It can be deoxidized to (S)-(+)-3-Hydroxytetrahydrofuran which is an important intermediate of anti-AIDS drugs. It is also used in the synthesis of S(-)-3-hydroxy-4-bromobutyric acid which is a potential stabilizer.

MOQ: 1kg
Packaging: 1kg/Aluminum film bag ; 25kg/one drum
Transportation: By Air(Chemical special line/DHL/UPS/TNT/FEDEX/EMS)
Delivery Time: 8-12 days

new gbl for sale

new gbl for sale CAS 7331-52-4
new gbl for sale CAS 7331-52-4

gbl for sale CAS 7331-52-4 product information:

Product Name: (S)-3-Hydroxy-gamma-butyrolactone
Synonyms: MFCD00211247;(4S)-4-Hydroxydihydro-2(3H)-furanone;2(3H)-Furanone, dihydro-4-hydroxy-, (4S)-;T5OVTJ DQ &&(S)-(-)- Form;(S)-4,5-Dihydro-4-hydroxy-2(3H)-furanone;(S)-(-)-3-Hydroxy-γ-butyrolactone;(S)-β-Hydroxy-γ-butyrolactone;(4S)-4-hydroxyoxolan-2-one;EINECS 434-990-4;3-Hydroxy-4-butanolide;(4S)-4-Hydroxydihydrofuran-2(3H)-one;(S)-3-Hydroxy-γ-butyrolactone
CAS NO: 7331-52-4
EINECS: 434-990-4
Molecular Formula: C4H6O3
Molecular Weight: 102.09
Melting Point: 1.24ºC
Boiling Point: 98-100 °C0.3 mm Hg(lit.)
Density: 1.241 g/mL at 25 °C(lit.)
Appearance: Transparent to pale yellow liquid
Storage: Sealed and stored in a cool, dry environment
Stability: Will not decompose if used and stored in accordance with specifications.
Applications: (S)-3-Hydroxy-γ-butyrolactone can be used as an anticancer drug resistance inhibitor.

How to make gbl?

γ-Butyrolactone is produced industrially by dehydrogenation of 1,4-butanediol at a temperature of 180–300 °C and atmospheric pressure in the presence of a copper catalyst.

Dehydrocyclization of 1,4-butanediol to form γ-butyrolactone in the presence of a copper catalyst

The yield of this process is approximately 95%. The purification takes place with a liquid-gas-phase extraction.

In the laboratory, it may also be obtained via the oxidation of tetrahydrofuran (THF), for example with aqueous sodium bromate. An alternative route proceeds from GABA via a diazonium intermediate.

gbl dosage:

A milliliter of pure GBL metabolizes to the equivalent 1.65 g of NaGHB, the common form, so doses are measured in the single milliliter range, either taken all at once or sipped over the course of a night.

ghb vs gbl:

What is it? 

  • G is the name given to the drugs GHB (gamma hydroxybutyrate) and GBL (gamma butyrolactone).
  • Other names include G, Gina, Liquid E and Liquid ecstasy.
  • GHB is an odourless, oily liquid, with a slightly salty taste, usually sold in small bottles or capsules.  The effects usually occur within 15-20 minutes and last up to 3-4 hours.
  • GBL is a liquid with a chemical smell and taste.  GBL is a precursor to GHB, which means that it is converted to GHB inside your body after swallowing.  It has a faster onset of action than GHB, and is often more potent – so a smaller dose is required to have the same effect.
  • G is usually swallowed in its liquid form, often mixed with water or a soft drink. Never mix G with alcohol as these 2 substances interact and can lead to death.  Less often it is snorted or inhaled.  Injecting G is dangerous.

What does it do? 

  • Both GHB and GBL are depressant drugs which can produce a high with small doses, and cause sedation with only slightly higher doses.  People report that G makes them feel euphoric, with a loss of inhibitions, increased confidence, and a higher sex drive.

What are the risks?

  • It is easy to overdose on G, as there is not much difference (less than one millilitre) between a dose that gets a person high, and a dose that has them “going under” – becoming unconscious and unresponsive.
  • Avoid mixing G with alcohol. This can increase the risk of going under, and delay the time it takes for G to take effect – interfering with safe dosing intervals.
  • A number of deaths have been caused by G. Death can result from overdose, or severe withdrawal syndrome.
  • Using G with other depressant drugs, such as alcohol, benzodiazepines and ketamine can increase the risk of going under and stopping breathing. In some cases, people might be hospitalised after using G.
  • G is addictive and dependence can develop quickly. Dependence mean people will develop withdrawal symptoms on stopping use, which can be severe and life-threatening.
  • The sedative properties of G can leave a person incoherent or comatose. People around you may take advantage of this to have sex with you without your consent.

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GBL CAS:7331-52-4

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