1-N-Boc-4-(Phenylamino)piperidine cas 125541-22-2
1-N-Boc-4-(Phenylamino)piperidine product information:
| Product Name | 1-N-Boc-4-(Phenylamino)piperidine |
| Synonyms | TERT-BUTYL 4-ANILINOTETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE;4-(Phenylamino)piperidine, N1-BOC protected;1-N-BOC-4-(PHENYLAMINO)PIPERIDINE;tert-butyl 4-anilinotetrahydro-1(2H)-pyridinecarboxylate (en) |
| CAS NO | 125541-22-2 |
| EINECS | 203-105-0 |
| Molecular Formula | C16H24N2O2 |
| Molecular Weight | 276.37 |
| Melting Point | 136-137 |
| Boiling Point | 400.6±38.0 °C(Predicted) |
| Flash Point | 196.1±26.8 °C |
| Density | 1.107±0.06 g/cm3(Predicted) |
| Assay | ≥99% |
| Grade | Pharmaceutical Grade |
| Solubility | DMF: 15mg/mL DMSO: 25mg/mL Ethanol: 25mg/mL Ethanol:PBS (pH 7.2) (1:1): 0.5mg/mL |
| Appearance | Pale Brown Solid |
| Storage | Keep away from light, in a cool and dry place, sealed |
| Usage | Intermediate in the preparation of Fentanyl derivatives |
1-N-Boc-4-(Phenylamino) piperidine uses
Intermediate in the preparation of Fentanyl derivatives.
The biochemical and physiological effects of Boc-Phe-Pip are not well-understood. However, it is known that Boc-Phe-Pip is a strong base, and its reaction with acids can result in the formation of a variety of products. These products can then be used in a variety of applications, including the synthesis of peptides and proteins, organic synthesis, and drug development.
The synthesis of Boc-Phe-Pip is typically carried out using a two-step process. The first step involves the reaction of piperidine with 4-bromobenzaldehyde in the presence of a base, such as sodium hydroxide. This reaction yields the desired product, 4-bromophenylpiperidine. The second step involves the reaction of 4-bromophenylpiperidine with Boc-anhydride in the presence of a base, such as sodium hydroxide, to yield the desired product, Boc-Phe-Pip.
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