Isopropylbenzylamine CAS 102-97-6

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N-Isopropylbenzylamine, can be used as an intermediate in the synthesis of pharmaceutical compounds,and as a precursor to the manufacture of some drugs. Due to it’s similarity in appearance and physical properties to methamphetamine, it has been recently come under consideration of DEA.

MOQ: 1kg
Packaging: 1kg/Aluminum film bag ; 25kg/one drum
Transportation: By Air(Chemical special line/DHL/UPS/TNT/FEDEX/EMS)
Delivery Time: 8-12 days

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isopropylbenzylamine

Isopropylbenzylamine CAS 102-97-6
Isopropylbenzylamine CAS 102-97-6

Isopropylbenzylamine CAS 102-97-6 product information:

Product Name: N-Isopropylbenzylamine
Synonyms: N-(1-Methylethyl)benzenemethanamine; (1-Methylethyl)(phenylmethyl)amine; Benzylisopropylamine; N-Benzyl-N-isopropylamine; N-Isopropyl-N-benzylamine; NSC 60295
CAS NO: 102-97-6
EINECS: 203-067-6
Molecular Formula: C₁₀H₁₅N
Molecular Weight: 149.23
Appearance: white columnar crystals
Storage: Refrigerator
Solubility: Chloroform (Slightly), Ethy Acetate (Slightly), Methanol (Slightly)
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isopropylbenzylamine symptoms

N-isopropylbenzylamine, an isomer of methamphetamine, has been used to adulterate methamphetamine, and distributed as fake “Ice” methamphetamine by illicit manufacturers, leading to a world problem of N-isopropylbenzylamine exposure. Though it is unclear whether N-isopropylbenzylamine has addictive potential like methamphetamine, N-isopropylbenzylamine users reported side effects such as headaches and confusion. However, the pharmacological targets and cytotoxicity of this chemical remained unknown. In vitro toxicity of N-isopropylbenzylamine and its toxicity-related targets were investigated in SN4741, SH-SY5Y or PC12 cell lines that model neurons. The cell viability was analyzed by using MTT assay after incubation with N-isopropylbenzylamine for 24 h in cells.
N-isopropylbenzylamine caused cell death with IC50 values at around 1-3 mM in these cell lines. N-isopropylbenzylamine time- and concentration-dependently facilitated the expression of neuronal nitric oxide synthase (nNOS), and increased intracellular nitric oxide (NO) in SN4741 cells. Furthermore, 7-nitroindazole, a specific inhibitor of nNOS, significantly prevented N-isopropylbenzylamine-induced toxicity in vitro. These results suggested that N-isopropylbenzylamine-induced toxicity is at least partially related to the increased intracellular NO levels and the activated nNOS.

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side effects of injecting isopropylbenzylamine

It currently is unknown to be a controlled substance in any other jurisdiction. Isopropylbenzylamine is not thought to have any stimulant effects in its own right, though anecdotal reports suggest that it may be associated with side effects such as headaches and confusion which are not typically associated with methamphetamine itself.[citation needed] The toxicity of N-isopropylbenzylamine has been studied as of 2022 and it has been found to produces toxicity via increasing nitric oxide in vitro. In this study, in vitro toxicity of N-isopropylbenzylamine and its toxicity-related targets were investigated in SN4741, SH-SY5Y or PC12 cell lines that model neurons. The study sounds an alarm for methamphetamine abusers and warns of the dangerousness of N-isopropylbenzylamine for public health.Other “cutting agents” found to have been used for methamphetamine include the related compounds methylbenzylamine and ethylbenzylamine, as well as dimethylsulfone.

removing isopropylbenzylamine

Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.

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